A condensed rapid review pass over the highest yield endocrine hormone axis and pathology facts for final week review.
40 cards · mixed cards · AI-written, checked twice. Edit anything.
- Which hypothalamic hormone stimulates ACTH release from the anterior pituitary?
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CRH (corticotropin-releasing hormone)- TRH from the hypothalamus stimulates release of which two anterior pituitary hormones?
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TSH and prolactin- What is the primary inhibitor of prolactin secretion?
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Dopamine- What is the core pathophysiology of type 2 diabetes mellitus?
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Insulin resistance combined with a relative insulin deficiency- Growth hormone's growth-promoting effects on bone and tissue are mediated mainly through ____, produced by the liver.
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IGF-1- Where does ADH (vasopressin) act in the kidney, and what is its effect?
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The collecting duct; it increases water reabsorption- What is the core pathophysiology of type 1 diabetes mellitus?
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Autoimmune destruction of pancreatic beta cells- What are the classic lab findings in SIADH?
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Hyponatremia with inappropriately concentrated urine in a euvolemic patient- How do central and nephrogenic diabetes insipidus differ in their response to desmopressin?
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Central DI responds (urine concentrates); nephrogenic DI does not respond- What is the TSH level in primary hyperthyroidism?
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Low (suppressed)- What is the TSH level in primary hypothyroidism?
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High (elevated)- Which autoantibody is responsible for Graves disease?
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TSH receptor-stimulating antibody (TSI)- Which two autoantibodies are classically associated with Hashimoto thyroiditis?
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Anti-thyroid peroxidase (anti-TPO) and anti-thyroglobulin antibodies- What is the most common cause of hypothyroidism worldwide?
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Iodine deficiency- What is the most common cause of hypothyroidism in iodine-sufficient (developed) countries?
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Hashimoto thyroiditis
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