Restrictive lung disease patterns and interstitial lung disease subtypes with their distinguishing imaging and biopsy findings.
About this set
34 basic cards for USMLE Step 1 Pulmonology. Set 4 of 4 in USMLE Pulmonology. It opens with "What happens to total lung capacity (TLC) in restrictive lung disease?" and "In restrictive lung disease, is the FEV1/FVC ratio decreased, normal, or". Study it alongside the other USMLE Step 1 sets below.
34 cards · basic cards · AI-written, checked twice. Edit anything.
- What happens to total lung capacity (TLC) in restrictive lung disease?
Show answer
It is decreased.- In restrictive lung disease, is the FEV1/FVC ratio decreased, normal, or increased?
Show answer
Normal or increased- What are the two main categories of restrictive lung disease?
Show answer
Intrinsic (interstitial) and extrinsic (extrapulmonary)- In intrinsic (interstitial) restrictive lung disease, is DLCO typically decreased or normal?
Show answer
Decreased- In extrinsic restrictive lung disease (chest wall or neuromuscular cause), is DLCO typically decreased or normal?
Show answer
Normal- Idiopathic pulmonary fibrosis shows the histologic pattern known as ____.
Show answer
usual interstitial pneumonia (UIP)- What is the classic biopsy hallmark of usual interstitial pneumonia (UIP)?
Show answer
Temporal heterogeneity with patchy fibroblastic foci- What HRCT finding is characteristic of idiopathic pulmonary fibrosis?
Show answer
Honeycombing- What is the typical distribution of fibrosis on imaging in idiopathic pulmonary fibrosis?
Show answer
Subpleural and basal predominant- Name the two antifibrotic drugs used to slow progression of idiopathic pulmonary fibrosis.
Show answer
Pirfenidone and nintedanib- What is the typical HRCT appearance of nonspecific interstitial pneumonia (NSIP)?
Show answer
Homogeneous ground-glass opacities- Nonspecific interstitial pneumonia (NSIP) is most commonly associated with which category of disease?
Show answer
Connective tissue disease (e.g., systemic sclerosis)- Compared to UIP, does NSIP have a better or worse prognosis?
Show answer
Better prognosis- What type of granuloma is seen on biopsy in sarcoidosis?
Show answer
Noncaseating granuloma- What is the classic chest x-ray finding in sarcoidosis?
Show answer
Bilateral hilar lymphadenopathy
FlashKeepers