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Biostatistics · USMLE Step 1 · Healthcare and Nursing

USMLE Biostatistics

Core biostatistics and epidemiology formulas including sensitivity, specificity, relative risk, and study design, as cloze cards with each term defined.

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35 cloze cards for USMLE Step 1 Biostatistics. Set 1 of 2 in USMLE Biostatistics. It opens with "Sensitivity is calculated as ____" and "Specificity is calculated as ____". Study it alongside the other USMLE Step 1 sets below.

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Sensitivity is calculated as ____.
Show answertrue positives / (true positives + false negatives)
Specificity is calculated as ____.
Show answertrue negatives / (true negatives + false positives)
Positive predictive value (PPV) is calculated as ____.
Show answertrue positives / (true positives + false positives)
Negative predictive value (NPV) is calculated as ____.
Show answertrue negatives / (true negatives + false negatives)
A highly sensitive test, when its result is negative, is used to ____ disease (mnemonic SnNout).
Show answerrule out
A highly specific test, when its result is positive, is used to ____ disease (mnemonic SpPin).
Show answerrule in
Prevalence is defined as the ____.
Show answerproportion of a population that has a disease at a given point in time
Incidence is defined as the ____.
Show answerrate at which new cases of a disease occur in a population over a specified time period
How does positive predictive value change as disease prevalence increases, if a test's sensitivity and specificity stay constant?
Show answerPPV increases
How does negative predictive value change as disease prevalence increases, if a test's sensitivity and specificity stay constant?
Show answerNPV decreases
Relative risk is calculated as ____.
Show answerincidence in the exposed group divided by incidence in the unexposed group
Relative risk is the primary risk measure calculated in which type of study design?
Show answerCohort study
In a 2x2 exposure/disease table with cells a, b, c, d, the odds ratio is calculated as ____.
Show answer(a x d) / (b x c)
An odds ratio closely approximates relative risk under what condition?
Show answerWhen the disease being studied is rare.
Odds ratio is the primary risk measure calculated in which type of study design?
Show answerCase-control study

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