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Biostatistics · USMLE Step 1 · Healthcare and Nursing

USMLE Biostatistics High-Yield Rapid Review

A condensed rapid review pass over the highest yield biostatistics and epidemiology formulas and study design facts for final week review.

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40 mixed cards for USMLE Step 1 Biostatistics. It opens with "What is the formula for sensitivity?" and "What is the formula for specificity?". Study it alongside the other USMLE Step 1 sets below.

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What is the formula for sensitivity?
Show answerTrue positives / (True positives + False negatives)
What is the formula for specificity?
Show answerTrue negatives / (True negatives + False positives)
What is the formula for positive predictive value (PPV)?
Show answerTrue positives / (True positives + False positives)
What is the formula for negative predictive value (NPV)?
Show answerTrue negatives / (True negatives + False negatives)
As disease prevalence increases, positive predictive value ____.
Show answerincreases
As disease prevalence increases, negative predictive value ____.
Show answerdecreases
Do sensitivity and specificity change with disease prevalence?
Show answerNo, they are intrinsic properties of the test itself
What is the formula for the positive likelihood ratio?
Show answerSensitivity / (1 - Specificity)
What is the formula for the negative likelihood ratio?
Show answer(1 - Sensitivity) / Specificity
What does the mnemonic SnNout mean?
Show answerA highly sensitive test, when negative, rules out disease
What does the mnemonic SpPin mean?
Show answerA highly specific test, when positive, rules in disease
In which study design is the odds ratio the appropriate measure of association?
Show answerCase-control studies
In which study design is relative risk the appropriate measure of association?
Show answerCohort studies
What is the formula for relative risk reduction (RRR)?
Show answer(Risk in unexposed - Risk in exposed) / Risk in unexposed
What is the formula for absolute risk reduction (ARR)?
Show answerRisk in unexposed (control) group minus risk in exposed (treatment) group

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