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Biostatistics · USMLE Step 1

USMLE Biostatistics High-Yield Rapid Review

A condensed rapid review pass over the highest yield biostatistics and epidemiology formulas and study design facts for final week review.

40 cards · basic cards · AI-written, checked twice. Edit anything.

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What is the formula for sensitivity?
True positives / (True positives + False negatives)
What is the formula for specificity?
True negatives / (True negatives + False positives)
What is the formula for positive predictive value (PPV)?
True positives / (True positives + False positives)
What is the formula for negative predictive value (NPV)?
True negatives / (True negatives + False negatives)
As disease prevalence increases, positive predictive value ____.
increases
As disease prevalence increases, negative predictive value ____.
decreases
Do sensitivity and specificity change with disease prevalence?
No, they are intrinsic properties of the test itself
What is the formula for the positive likelihood ratio?
Sensitivity / (1 - Specificity)
What is the formula for the negative likelihood ratio?
(1 - Sensitivity) / Specificity
What does the mnemonic SnNout mean?
A highly sensitive test, when negative, rules out disease
What does the mnemonic SpPin mean?
A highly specific test, when positive, rules in disease
In which study design is the odds ratio the appropriate measure of association?
Case-control studies
In which study design is relative risk the appropriate measure of association?
Cohort studies
What is the formula for relative risk reduction (RRR)?
(Risk in unexposed - Risk in exposed) / Risk in unexposed
What is the formula for absolute risk reduction (ARR)?
Risk in unexposed (control) group minus risk in exposed (treatment) group

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