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Endocrine · Clinical Endocrinology

Endocrinology: Diabetes Clinical Management

Insulin regimen selection, monitoring targets, and diabetic complication screening in clinical practice, distinct from the mechanism-of-action focus of the pharmacology deck.

40 cards · basic cards · AI-written, checked twice. Edit anything.

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What is the first-line pharmacologic agent for type 2 diabetes in most patients?
Metformin
What is a basal-bolus insulin regimen?
Long-acting background insulin plus short or rapid-acting insulin given before meals
Name a commonly used long-acting (basal) insulin.
Insulin glargine (or detemir, degludec)
Name a commonly used rapid-acting insulin.
Insulin lispro (or aspart, glulisine)
What is a typical starting total daily insulin dose for a newly diagnosed patient?
About 0.5 units per kg per day
In a basal-bolus regimen, what percentage of total daily insulin is usually given as basal?
About 50 percent
What does the 1800 rule estimate?
The insulin sensitivity (correction) factor: how much 1 unit of rapid-acting insulin lowers blood glucose
What does the 500 rule estimate?
The insulin-to-carbohydrate ratio: grams of carbohydrate covered by 1 unit of insulin
The ADA recommends a general HbA1c goal of less than ____ for most nonpregnant adults with diabetes.
7%
What HbA1c goal is often used for older or frail adults with diabetes?
Less than 8% (individualized, less strict target)
The ADA fasting and preprandial glucose target range is ____.
80 to 130 mg/dL
The ADA peak postprandial glucose target is less than ____.
180 mg/dL
How often should HbA1c be checked in a patient at goal with stable therapy?
Every 6 months
How often should HbA1c be checked in a patient not at goal or with recently changed therapy?
Every 3 months
What blood glucose level defines hypoglycemia?
Less than 70 mg/dL

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