Shock states, sepsis, DIC, trauma, ethics, advocacy, moral distress and the AACN Synergy Model.
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- What hemodynamic pattern defines cardiogenic shock?
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Low cardiac output with high systemic vascular resistance (pump failure).
- What hemodynamic pattern defines hypovolemic shock?
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Low preload, low cardiac output, and high systemic vascular resistance.
- What hemodynamic pattern defines early septic (distributive) shock?
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Low systemic vascular resistance with normal or high cardiac output (warm shock).
- What causes obstructive shock?
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A physical blockage to blood flow, such as tension pneumothorax, cardiac tamponade, or massive pulmonary embolism.
- What is the hallmark hemodynamic finding in neurogenic shock?
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Hypotension with bradycardia from loss of sympathetic tone.
- What triad of findings suggests anaphylactic shock?
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Hypotension, bronchospasm or stridor, and urticaria or angioedema after an allergen exposure.
- What is the first-line drug for anaphylactic shock?
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Intramuscular epinephrine.
- What serum lactate level, combined with vasopressor-dependent hypotension, supports a diagnosis of septic shock?
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Greater than 2 mmol/L.
- What is SIRS?
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Systemic Inflammatory Response Syndrome, a nonspecific inflammatory reaction (fever, tachycardia, tachypnea, abnormal white blood cell count) that can occur with or without infection.
- How does sepsis differ from simple SIRS?
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Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection.
- Within what time frame should broad-spectrum antibiotics be started after recognizing septic shock?
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Within 1 hour.
- What initial fluid bolus is recommended for sepsis-induced hypoperfusion?
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30 mL/kg of crystalloid within the first 3 hours.
- What vasopressor is first-line for septic shock?
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Norepinephrine.
- Why is serial lactate clearance monitored during septic shock resuscitation?
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It reflects improving tissue perfusion and response to treatment.
- What causes disseminated intravascular coagulation (DIC)?
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Widespread activation of the clotting cascade that consumes clotting factors and platelets, causing simultaneous clotting and bleeding.