Epidemiology, risk factors, screening, staging concepts, biomarkers such as HER2 and EGFR, and first-line treatment approaches for the four most common solid cancers.
40 cards · basic cards · AI-written, checked twice. Edit anything.
- What is the most common cancer in women worldwide (excluding skin cancer)?
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Breast cancer
- BRCA1 and BRCA2 mutations increase the risk of which two cancers?
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Breast and ovarian cancer
- What is the standard screening test for breast cancer in average-risk women?
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Mammography
- At what age do most guidelines recommend starting routine mammography screening in average-risk women?
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Age 40 to 50
- What receptor, when overexpressed, defines HER2-positive breast cancer?
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Human epidermal growth factor receptor 2 (HER2/neu)
- Which targeted drug is first-line therapy for HER2-positive breast cancer?
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Trastuzumab
- What is the first-line treatment approach for hormone receptor-positive breast cancer?
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Endocrine therapy, such as tamoxifen or an aromatase inhibitor
- What is triple-negative breast cancer?
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Breast cancer lacking ER, PR, and HER2 expression
- What is the most common histologic type of breast cancer?
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Invasive ductal carcinoma
- Breast cancer staging is primarily based on which three TNM factors?
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Tumor size, lymph node involvement, and distant metastasis
- What is the leading cause of lung cancer worldwide?
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Cigarette smoking
- What are the two broad histologic categories of lung cancer?
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Small cell lung cancer and non-small cell lung cancer
- Which type of lung cancer accounts for about 85 percent of cases?
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Non-small cell lung cancer
- What imaging modality is recommended for lung cancer screening in high-risk smokers?
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Low-dose CT scan
- Name a targeted drug used for EGFR-mutant non-small cell lung cancer.
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Osimertinib