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Epidemiology · Public Health

Epidemiology: Measures of Disease Frequency and Association

Incidence, prevalence, relative risk, and odds ratio as cloze cards with each formula and variable defined.

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Incidence measures the number of ____ cases of a disease occurring in a population during a specified time period.
new
Cumulative incidence = number of new cases during a time period divided by ____.
the population at risk at the start of the period
Incidence rate (incidence density) = number of new cases divided by ____.
total person-time at risk
What is person-time?
The sum of the amount of time each individual in a population was at risk and under observation (e.g., person-years).
Prevalence measures the proportion of a population that has a disease at a given point or period, including both ____ cases.
new and pre-existing (old)
Point prevalence = number of existing cases at a specific point in time divided by ____.
total population at that time
Period prevalence = number of cases existing at any time during a specified interval divided by ____.
the average (or mid-interval) population during that interval
In a population at steady state, prevalence is approximately equal to ____ (P is approximately I x D).
incidence rate multiplied by average duration of disease
Name one way prevalence can increase without any change in incidence.
Improved survival or treatment that lengthens the average duration of disease.
In calculating incidence, the population at risk in the denominator should exclude people who already ____.
have the disease
Relative risk (risk ratio) compares the risk of disease in the ____ to the risk in the unexposed group.
exposed group
Relative risk = risk of disease in the exposed group divided by ____.
risk of disease in the unexposed group
What does a relative risk of 1.0 mean?
No association: the exposed and unexposed groups have the same risk of disease.
What does a relative risk greater than 1.0 mean?
The exposure is associated with an increased risk of disease.
What does a relative risk less than 1.0 mean?
The exposure is associated with a decreased risk of disease (a protective effect).

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