Species-specific drug cautions, anesthetic protocols, NSAID safety, and toxins such as chocolate, xylitol, lilies and rodenticides.
40 cards · basic cards · AI-written, checked twice. Edit anything.
- Why are Collies and other MDR1-mutant breeds unusually sensitive to ivermectin?
Show answer
A P-glycoprotein (MDR1) defect lets ivermectin cross the blood-brain barrier, causing neurotoxicity.- What anesthetic premedication should be used cautiously in Boxers due to breed sensitivity?
Show answer
Acepromazine, which can cause exaggerated bradycardia and syncope in Boxers.- Why do Greyhounds and other sighthounds have prolonged recovery from thiobarbiturate anesthesia?
Show answer
Their low body fat limits the drug's redistribution into fat stores, so it stays active longer.- What is the hallmark toxic effect of acetaminophen in cats?
Show answer
Methemoglobinemia and Heinz body formation, since cats lack efficient glucuronidation.- Why do cats metabolize many drugs (NSAIDs, acetaminophen) more slowly than dogs?
Show answer
Cats have deficient glucuronyl transferase activity for glucuronidation.- What common toxicity occurs when dog-only permethrin flea products are applied to cats?
Show answer
Permethrin toxicity causing severe tremors and seizures, since cats lack the enzymes to detoxify it.- What orthopedic adverse effect can fluoroquinolones cause in young, growing dogs?
Show answer
Cartilage lesions and erosions in weight-bearing joints.- What ocular adverse effect is associated with high-dose enrofloxacin in cats?
Show answer
Acute retinal degeneration and blindness.- What cosmetic adverse effect can tetracyclines cause if given to young animals?
Show answer
Permanent yellow-brown discoloration of developing teeth.- What adverse effect can occur with high-dose or prolonged metronidazole use?
Show answer
Neurotoxicity, including ataxia, nystagmus, and seizures.- Why should alpha-2 agonists like xylazine be used cautiously in pregnant cattle?
Show answer
They can induce premature parturition or abortion by increasing uterine tone.- Why must handlers wear gloves when administering chloramphenicol?
Show answer
It carries a rare but serious risk of aplastic anemia in humans who absorb it.- Why is griseofulvin contraindicated in pregnant queens?
Show answer
It is teratogenic and can cause severe birth defects in kittens.- Which dog breed is known for a hypersensitivity reaction to potentiated sulfonamides?
Show answer
The Doberman Pinscher.- Why are lincosamides (lincomycin, clindamycin) contraindicated in rabbits, guinea pigs, and horses?
Show answer
They can cause fatal enterotoxemia by disrupting normal gut flora.
FlashKeepers