Prenatal visit schedules, trimester-specific screening tests, and normal pregnancy physiology tested on USMLE Step 2 CK.
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- How often are prenatal visits scheduled from weeks 4 to 28 of gestation?
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Every 4 weeks- How often are prenatal visits scheduled from weeks 28 to 36 of gestation?
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Every 2 weeks- How often are prenatal visits scheduled from weeks 36 to 40 (until delivery)?
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Every week- What is the formula for Naegele's rule when estimating the due date (EDD)?
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Take the first day of the last menstrual period, subtract 3 months, then add 7 days (and 1 year)- In early pregnancy, what is the most accurate method for estimating gestational age?
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First trimester ultrasound (crown-rump length)- What three components make up first trimester combined screening for aneuploidy (11-14 weeks)?
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Nuchal translucency ultrasound, PAPP-A, and beta-hCG- What noninvasive prenatal screening test can be performed starting around 10 weeks using a maternal blood sample?
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Cell-free fetal DNA testing (NIPT)- What four analytes make up the second trimester quad screen?
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AFP, hCG, estriol, and inhibin A- During what gestational age window is the quad screen performed?
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15 to 20 weeks (ideally 16 to 18 weeks)- An elevated maternal serum AFP is associated with which fetal conditions?
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Neural tube defects, abdominal wall defects (gastroschisis or omphalocele), and multiple gestation- A low maternal serum AFP is classically associated with which chromosomal condition?
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Down syndrome (trisomy 21)- At what gestational age is chorionic villus sampling (CVS) performed?
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10 to 13 weeks- At what gestational age is genetic amniocentesis typically performed?
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15 to 20 weeks- At what gestational age is the fetal anatomy survey ultrasound performed?
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18 to 20 weeks- At what gestational age is the 1-hour glucose challenge test (GCT) routinely performed?
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24 to 28 weeks
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