Prenatal visit schedules, trimester-specific screening tests, and normal pregnancy physiology tested on USMLE Step 2 CK.
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- How often are prenatal visits scheduled from weeks 4 to 28 of gestation?
- Every 4 weeks
- How often are prenatal visits scheduled from weeks 28 to 36 of gestation?
- Every 2 weeks
- How often are prenatal visits scheduled from weeks 36 to 40 (until delivery)?
- Every week
- What is the formula for Naegele's rule when estimating the due date (EDD)?
- Take the first day of the last menstrual period, subtract 3 months, then add 7 days (and 1 year)
- In early pregnancy, what is the most accurate method for estimating gestational age?
- First trimester ultrasound (crown-rump length)
- What three components make up first trimester combined screening for aneuploidy (11-14 weeks)?
- Nuchal translucency ultrasound, PAPP-A, and beta-hCG
- What noninvasive prenatal screening test can be performed starting around 10 weeks using a maternal blood sample?
- Cell-free fetal DNA testing (NIPT)
- What four analytes make up the second trimester quad screen?
- AFP, hCG, estriol, and inhibin A
- During what gestational age window is the quad screen performed?
- 15 to 20 weeks (ideally 16 to 18 weeks)
- An elevated maternal serum AFP is associated with which fetal conditions?
- Neural tube defects, abdominal wall defects (gastroschisis or omphalocele), and multiple gestation
- A low maternal serum AFP is classically associated with which chromosomal condition?
- Down syndrome (trisomy 21)
- At what gestational age is chorionic villus sampling (CVS) performed?
- 10 to 13 weeks
- At what gestational age is genetic amniocentesis typically performed?
- 15 to 20 weeks
- At what gestational age is the fetal anatomy survey ultrasound performed?
- 18 to 20 weeks
- At what gestational age is the 1-hour glucose challenge test (GCT) routinely performed?
- 24 to 28 weeks