Pap and HPV screening intervals, colposcopy, CIN management, hysterectomy types, endometrial sampling and common gynecologic surgical procedures.
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- At what age should cervical cancer screening begin in average-risk women?
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Age 21.
- What is the recommended cervical cancer screening interval for average-risk women ages 21 to 29?
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Pap smear (cytology) alone every 3 years.
- What is the preferred cervical cancer screening strategy for average-risk women ages 30 to 65?
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Co-testing with Pap smear and HPV testing every 5 years.
- At what age can average-risk women stop cervical cancer screening?
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Age 65, if they have adequate prior negative screening history.
- What counts as adequate prior negative screening to stop Pap testing at age 65?
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Two consecutive negative co-tests or three consecutive negative Pap tests within the prior 10 years, the most recent within 5 years.
- Should a woman who had a hysterectomy for benign disease, with the cervix removed, continue cervical cancer screening?
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No, screening is not needed if there is no history of high-grade dysplasia or cancer.
- Which two HPV types cause the majority of cervical cancers?
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HPV 16 and HPV 18.
- What does a Pap result of ASC-US stand for?
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Atypical squamous cells of undetermined significance.
- What is the recommended next step after an ASC-US Pap result in a woman 25 or older?
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Reflex HPV testing, with colposcopy if HPV positive.
- What does a Pap result of LSIL stand for?
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Low-grade squamous intraepithelial lesion.
- What is the recommended management for an HSIL Pap result?
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Referral for colposcopy, or an excisional procedure directly.
- What is colposcopy?
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Direct visualization of the cervix under magnification to identify abnormal tissue.
- Why is acetic acid applied to the cervix during colposcopy?
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It turns abnormal (dysplastic) tissue acetowhite, making it visible.
- What is the Schiller test performed during colposcopy?
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Applying Lugol's iodine; normal glycogen-rich tissue stains brown, while abnormal tissue does not take up the stain.
- What does CIN stand for?
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Cervical intraepithelial neoplasia.