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Musculoskeletal and Dermatology · USMLE Step 1

USMLE Dermatology and Musculoskeletal High-Yield Review

A condensed rapid review pass over the highest yield dermatology and musculoskeletal facts for final week review.

40 cards · basic cards · AI-written, checked twice. Edit anything.

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What skin finding is the Auspitz sign?
Pinpoint bleeding when a psoriatic scale is scraped off
What is the Koebner phenomenon?
New psoriatic lesions forming at sites of skin trauma
Is the Nikolsky sign positive or negative in pemphigus vulgaris?
Positive
Is the Nikolsky sign positive or negative in bullous pemphigoid?
Negative
Pemphigus vulgaris (autoantibody target)
Desmoglein 3
Bullous pemphigoid (autoantibody target)
BP180 (a hemidesmosome protein)
At what skin layer does pemphigus vulgaris form its blister?
Intraepidermal, just above the basal layer (suprabasal)
At what skin layer does bullous pemphigoid form its blister?
Subepidermal, at the dermal-epidermal junction
What classic lesion shape is seen in erythema multiforme?
Target-shaped (bullseye) lesions
Stevens-Johnson syndrome involves what percentage of body surface area?
Less than 10 percent
Toxic epidermal necrolysis involves what percentage of body surface area?
More than 30 percent
____ is the most common type of skin cancer overall.
Basal cell carcinoma
What classic appearance does basal cell carcinoma have?
A pearly papule with telangiectasias
What precancerous lesion often precedes squamous cell carcinoma of the skin?
Actinic keratosis
In the ABCDE mnemonic for melanoma, E stands for ____.
Evolution or change over time

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