Statins and lipid agents, anticoagulants, antiplatelets, diuretics, antianginals and antiarrhythmics among the top 200 drugs.
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- Atorvastatin
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Lipitor
- What enzyme do statins inhibit?
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HMG-CoA reductase
- What serious muscle-related adverse effect is associated with statins?
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Myopathy, which can progress to rhabdomyolysis
- What is the brand name for rosuvastatin?
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Crestor
- Why is simvastatin typically taken in the evening?
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Because cholesterol synthesis is highest overnight
- How does ezetimibe lower cholesterol?
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It blocks absorption of cholesterol at the small intestine brush border
- What is the brand name for ezetimibe?
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Zetia
- Fenofibrate belongs to which class of lipid-lowering drugs?
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Fibrates
- Cholestyramine belongs to which drug class?
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Bile acid sequestrant (resin)
- What common side effect limits niacin use for dyslipidemia?
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Flushing (skin redness and warmth)
- What is warfarin's mechanism of action?
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It antagonizes vitamin K, reducing synthesis of clotting factors II, VII, IX, and X
- What lab value is used to monitor warfarin therapy?
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INR (International Normalized Ratio)
- What is the antidote for warfarin overdose or excessive bleeding?
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Vitamin K (phytonadione)
- What drug reverses the effects of heparin?
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Protamine sulfate
- What is the brand name for enoxaparin?
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Lovenox