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NAPLEX · NAPLEX

NAPLEX Mental Health Pharmacotherapy

Depression, anxiety, and bipolar disorder drug therapy selection and monitoring parameters tested on the NAPLEX.

34 cards · basic cards · AI-written, checked twice. Edit anything.

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What is the first-line drug class for treating major depressive disorder (MDD)?
SSRIs (selective serotonin reuptake inhibitors)
Which SSRI has the longest half-life among the class?
Fluoxetine
Which SSRI has the most anticholinergic and sedating side effect profile?
Paroxetine
Which SSRI is most associated with GI side effects such as diarrhea?
Sertraline
What is the maximum recommended daily dose of citalopram due to QT prolongation risk?
40 mg per day (20 mg per day in patients over 60 or with hepatic impairment)
What side effect is commonly shared by SSRIs and SNRIs as a class?
Sexual dysfunction
Serotonin syndrome presents with altered mental status, autonomic instability, and ____.
neuromuscular abnormalities such as clonus, hyperreflexia, and tremor
Venlafaxine and duloxetine belong to which antidepressant class?
SNRIs (serotonin-norepinephrine reuptake inhibitors)
What vital sign should be monitored with venlafaxine due to a dose-dependent effect?
Blood pressure (can cause hypertension at higher doses)
Bupropion should be avoided in patients with which two conditions?
Seizure disorder and eating disorders (such as bulimia)
What are the two most common side effects of mirtazapine?
Weight gain and sedation
Why must patients on MAOIs avoid tyramine-rich foods?
To prevent a hypertensive crisis
How many weeks does it typically take to see the full effect of an antidepressant?
4 to 6 weeks
What drug class is used first-line for short-term relief of acute anxiety symptoms?
Benzodiazepines
Which anxiolytic has a delayed onset of 2 to 4 weeks and low abuse potential?
Buspirone

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