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Biology · MCAT

MCAT Biology: Biochemistry and Metabolism

Biochemical pathways, enzymes, and metabolism concepts relevant to the MCAT biological sciences section. Front: the term or pathway. Back: a plain-language definition or function.

40 cards · basic cards · AI-written, checked twice. Edit anything.

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What is the net ATP yield from glycolysis per glucose molecule (substrate-level phosphorylation only)?
2 ATP
Where in the cell does glycolysis take place?
The cytoplasm (cytosol)
What is the rate-limiting enzyme of glycolysis?
Phosphofructokinase-1 (PFK-1)
Which enzyme complex converts pyruvate into acetyl-CoA?
Pyruvate dehydrogenase complex
Where is the pyruvate dehydrogenase complex located?
The mitochondrial matrix
What is another name for the citric acid cycle?
The Krebs cycle (also called the TCA cycle)
Where does the citric acid cycle take place?
The mitochondrial matrix
How many NADH molecules are produced per acetyl-CoA that enters the citric acid cycle?
3 NADH
What is the rate-limiting enzyme of the citric acid cycle?
Isocitrate dehydrogenase
Where is the electron transport chain located?
The inner mitochondrial membrane
What is the final electron acceptor of the electron transport chain?
Oxygen
By what mechanism does ATP synthase generate ATP?
Chemiosmosis, using the flow of protons down their electrochemical gradient
What reaction does Complex IV of the electron transport chain catalyze?
Reduction of oxygen to water
Approximately how much total ATP does complete aerobic oxidation of one glucose molecule yield?
About 30 to 32 ATP
What is gluconeogenesis?
The synthesis of new glucose from non-carbohydrate precursors such as lactate, glycerol, and amino acids

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