Biochemistry · MCAT

MCAT Biochem Rapid Review

A condensed rapid review pass over the highest yield MCAT biochemistry facts for final week review.

40 cards · basic cards · AI-written, checked twice. Edit anything.

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Which standard amino acid lacks a chiral center?
Glycine
What chirality are amino acids found in mammalian proteins?
L-configuration
What type of reaction forms a peptide bond between two amino acids?
Dehydration (condensation) reaction
Why does the peptide bond have restricted rotation?
It has partial double bond character from resonance
What does a protein's primary structure describe?
The linear sequence of amino acids
Name the two common secondary structure motifs in proteins.
Alpha helix and beta sheet
What stabilizes protein secondary structure?
Hydrogen bonds between backbone atoms
What does tertiary structure describe?
The overall 3D folding of a single polypeptide chain
What interactions stabilize tertiary protein structure?
Hydrophobic interactions, ionic bonds, hydrogen bonds, and disulfide bonds among side chains
What does quaternary structure describe?
The arrangement of multiple polypeptide subunits into one functional protein
Between which amino acid residues do disulfide bonds form?
Cysteine residues
How do enzymes increase reaction rate?
By lowering the activation energy
Are enzymes consumed or permanently altered during a reaction?
No, they are not consumed and can be reused
In Michaelis-Menten kinetics, what does Km represent?
The substrate concentration at which reaction velocity is half of Vmax
How does a competitive inhibitor affect Km and Vmax?
Increases apparent Km, Vmax stays the same

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