TB screening tests, latent versus active treatment regimens, drug side effects, hepatitis A through E serology and treatment.
40 cards · basic cards · AI-written, checked twice. Edit anything.
- What does the tuberculin skin test (TST/Mantoux) measure?
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Delayed-type hypersensitivity (cell-mediated immune response) to injected PPD antigen- What does an interferon-gamma release assay (IGRA) measure?
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Interferon-gamma released by T cells in response to TB-specific antigens (ESAT-6, CFP-10)- What TST induration size is considered positive in HIV-positive patients or close TB contacts?
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5 mm or greater- What TST induration size is considered positive in recent immigrants and healthcare workers?
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10 mm or greater- What TST induration size is considered positive in a person with no known TB risk factors?
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15 mm or greater- What is the main advantage of IGRA over the tuberculin skin test?
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It is not affected by prior BCG vaccination- How is latent TB infection defined?
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A positive TB test with no symptoms, a normal chest x-ray, and no ability to spread the infection- What is the preferred regimen for treating latent TB infection?
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Rifapentine plus isoniazid once weekly for 3 months (3HP)- What is an alternative single-drug regimen for latent TB infection?
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Isoniazid daily for 9 months- What latent TB regimen is used when isoniazid cannot be given?
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Rifampin daily for 4 months- What four drugs make up the intensive phase of active TB treatment?
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Rifampin, isoniazid, pyrazinamide, and ethambutol- How long does the intensive phase of standard active TB treatment last?
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2 months- What two drugs make up the continuation phase of active TB treatment?
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Isoniazid and rifampin- How long does the continuation phase of standard active TB treatment last?
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4 months- What is the total duration of standard active TB drug therapy?
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6 months
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