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Infectious Disease · Clinical Infectious Disease · Healthcare and Nursing

Infectious Disease HIV and Opportunistic Infections

HIV testing, antiretroviral classes, CD4 thresholds for prophylaxis, opportunistic infection organisms, PrEP and PEP.

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39 basic cards for Clinical Infectious Disease Infectious Disease. It opens with "What blood test is recommended as the initial screening test for HIV infection?" and "Which specific HIV antigen does the 4th generation screening test detect in". More Healthcare and Nursing decks are listed below.

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What blood test is recommended as the initial screening test for HIV infection?
Show answerA 4th generation antigen/antibody combination immunoassay
Which specific HIV antigen does the 4th generation screening test detect in addition to antibodies?
Show answerp24 antigen
About how long is the window period for a 4th generation HIV antigen/antibody test?
Show answerAbout 2 to 4 weeks after exposure
Which older HIV confirmatory test has largely been replaced in current testing algorithms?
Show answerWestern blot
What test now serves as the HIV confirmatory test in place of Western blot?
Show answerHIV-1/HIV-2 antibody differentiation immunoassay
Which test best detects acute HIV infection before antibodies have formed?
Show answerHIV RNA (viral load) test
At what CD4 count should prophylaxis against Pneumocystis jirovecii pneumonia (PCP) begin?
Show answerCD4 count less than 200 cells/mcL
What is the first-line drug for PCP prophylaxis?
Show answerTrimethoprim-sulfamethoxazole (TMP-SMX)
At what CD4 count should prophylaxis against Mycobacterium avium complex (MAC) begin?
Show answerCD4 count less than 50 cells/mcL
What drug is used for MAC prophylaxis in advanced HIV?
Show answerAzithromycin, given weekly
At what CD4 count should toxoplasmosis prophylaxis be considered in a Toxoplasma IgG-positive patient?
Show answerCD4 count less than 100 cells/mcL
What is an alternative PCP prophylaxis option for a patient with a sulfa allergy?
Show answerDapsone, atovaquone, or aerosolized pentamidine
Which organism causes Pneumocystis pneumonia in AIDS patients?
Show answerPneumocystis jirovecii, a fungus
Which organism causes toxoplasma encephalitis in AIDS patients?
Show answerToxoplasma gondii, a protozoan parasite
Which virus causes retinitis in patients with advanced AIDS?
Show answerCytomegalovirus (CMV)

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